SCHEMBL891729

SCHEMBL891729

O=C(O)[C@H](O)[C@@H](CO)OP(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PGD P52209 4/20 0.47
PGK1 P00558 1/20 0.41
PGK2 P07205 1/20 0.41
PDE4A P27815 1/20 0.39
PTPN1 P18031 1/20 0.37
TSHR P16473 2/20 0.36
OR51E2 Q9H255 1/20 0.36
CYP2C9 P11712 1/20 0.34
LAP3 P28838 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2229219 0.82 PTPN1 (0.39) PGDPGK1PGK2PTPN1
SCHEMBL7868485 0.82 CYP2C9 (0.38) PGDPGK1PGK2PTPN1TSHR
SCHEMBL8854308 0.78 PTPN1 (0.41) PGDPGK1PGK2PTPN1
SCHEMBL28881933 0.78 USP2 (0.39) PGDPGK1PGK2PTPN1LAP3
SCHEMBL850647 0.78 USP2 (0.39) PGDPGK1PGK2PTPN1LAP3
SCHEMBL850646 0.78 USP2 (0.39) PGDPGK1PGK2PTPN1LAP3
SCHEMBL28033517 0.76 PTPN1 (0.43) PGDPGK1PGK2PTPN1
SCHEMBL2216482 0.76 PTPN1 (0.43) PGDPGK1PGK2PTPN1
SCHEMBL7803701 0.75 CYP2C9 (0.44) PGDPTPN1TSHRCYP2C9
SCHEMBL7764499 0.73 PDE4A (0.52) PGDPGK1PGK2PDE4ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10329575-B2 Regulatory sequence for plants CERES, INC. (US) 2019-06-25 US disclosed
US-20180273985-A1 CELL-FREE PRODUCTION OF BUTANOL GREENLIGHT BIOSCIENCES, INC. 2018-09-27 US disclosed
US-20180223303-A1 SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY CERES INC (US) 2018-08-09 US disclosed
US-20170037426-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby ALEXANDROV NICKOLAI (US) 2017-02-09 US disclosed
WO-2016149631-A2 CELL-FREE PRODUCTION OF BUTANOL GREENLIGHT BIOSCIENCES, INC. (US) 2016-09-22 WO disclosed
US-20160076046-A1 PROMOTER, PROMOTER CONTROL ELEMENTS, AND COMBINATIONS, AND USES THEREOF CERES, INC. (US) 2016-03-17 US disclosed
US-9029523-B2 Promoter, promoter control elements, and combinations, and uses thereof CERES, INC. (US) 2015-05-12 US disclosed
US-20150033417-A9 Promoter, promoter control elements, and combinations, and uses thereof ALEXANDROV NICKOLAI (US) 2015-01-29 US disclosed
US-8877916-B2 Promoter, promoter control elements, and combinations, and uses thereof CERES, INC. (US) 2014-11-04 US disclosed
US-20120159672-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby CERES, INC. 2012-06-21 US disclosed
US-20120084885-A1 Promoter, promoter control elements, and combinations, and uses thereof ALEXANDROV NICKOLAI (US) 2012-04-05 US disclosed
US-20110191912-A1 Promoter, promoter control elements, and combinations, and uses thereof ALEXANDROV NICKOLAI 2011-08-04 US disclosed
US-20100037355-A1 SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY CERES, INC (US) 2010-02-11 US disclosed
US-20090265815-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded therapy ALEXANDROV NICKOLAI 2009-10-22 US disclosed
US-20070214517-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby CERES, INC. (US) 2007-09-13 US disclosed
US-20060150283-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby ALEXANDROV NICKOLAI 2006-07-06 US disclosed
US-20060048240-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby ALEXANDROV NICKOLAI 2006-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037426-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby RNGTT, CPSF1, CPSF6 PGD 3517/4885PGK1 2837/4885PGK2 2951/4885
US-20150033417-A9 Promoter, promoter control elements, and combinations, and uses thereof RNGTT, GTF3C5, GTF3C1 PGD 3339/4885PGK1 2510/4885PGK2 2749/4885
US-20120084885-A1 Promoter, promoter control elements, and combinations, and uses thereof RNGTT, GTF3C5, GTF3C1 PGD 3368/4885PGK1 2484/4885PGK2 2702/4885
US-20070214517-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby RNGTT, CPSF1, CPSF6 PGD 3517/4885PGK1 2837/4885PGK2 2951/4885
US-20110191912-A1 Promoter, promoter control elements, and combinations, and uses thereof RNGTT, GTF3C5, GTF3C1 PGD 3339/4885PGK1 2510/4885PGK2 2749/4885
US-20120159672-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby RNGTT, CPSF1, CPSF6 PGD 3517/4885PGK1 2837/4885PGK2 2951/4885
US-20100037355-A1 SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY RNGTT, CPSF1, CPSF6 PGD 3517/4885PGK1 2837/4885PGK2 2951/4885
US-20060048240-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby RNGTT, CPSF1, CPSF6 PGD 3517/4885PGK1 2837/4885PGK2 2951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.