Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.38 |
| ▸ | TEK | Q02763 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876973 | 0.86 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8017796 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8019097 | 0.72 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPK1 | |
| SCHEMBL22335210 | 0.71 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPK1 | |
| SCHEMBL5036894 | 0.68 | TGM2 (0.69) | SMN1; SMN2EPHX2NR1H4EGFRFYN | |
| SCHEMBL9078038 | 0.68 | TGM2 (0.63) | CYP2C19EPHX2NR1H4NPC1RAB9A | |
| SCHEMBL7873757 | 0.68 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2C9CYP2C19EPHB4 | |
| SCHEMBL8956291 | 0.68 | RAB9A (0.51) | SMN1; SMN2ALDH1A1CYP3A4CYP2C19EPHX2 | |
| SCHEMBL25113190 | 0.67 | ALDH1A1 (0.45) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPK1 | |
| SCHEMBL19860763 | 0.66 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-5780642-A | NON-STEROIDAL ANTIINFLAMMATORY AGENT WHICH BLOCKS RELEASE OF ARACHIDONIC ACID FROM PHOSPHOLIPIDS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |