Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 10/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868667 | 0.86 | TRPV1 (0.43) | TBXAS1NAMPTESRRBESRRGHDAC4 | |
| SCHEMBL7875230 | 0.83 | TBXAS1 (0.37) | TBXAS1NAMPTHRH4 | |
| SCHEMBL9021023 | 0.80 | HPGD (0.48) | TBXAS1NAMPTGAASMN1; SMN2 | |
| SCHEMBL9368177 | 0.79 | NAMPT (0.43) | TBXAS1NAMPT | |
| SCHEMBL7868671 | 0.79 | TAAR1 (0.43) | TBXAS1NAMPTHRH4GAASMN1; SMN2 | |
| SCHEMBL7879544 | 0.78 | ALDH1A1 (0.44) | TBXAS1NAMPTSMN1; SMN2 | |
| SCHEMBL7873879 | 0.77 | TBXAS1 (0.38) | TBXAS1NAMPT | |
| SCHEMBL7875358 | 0.76 | TBXAS1 (0.36) | TBXAS1NAMPTHRH4 | |
| SCHEMBL9367836 | 0.76 | TERT (0.41) | TBXAS1NAMPT | |
| SCHEMBL7876928 | 0.75 | NPC1 (0.44) | NAMPTHDAC4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |