Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405864 | 1.00 | KMO (0.68) | KMOSLC6A4SLC6A3HPGDKDM4E | |
| SCHEMBL19660202 | 0.86 | KMO (0.56) | KMOSLC6A4SLC6A3HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL7899395 | 0.82 | KMO (0.69) | KMOSLC6A4SLC6A3HPGDKDM4E | |
| SCHEMBL4386002 | 0.81 | KMO (1.00) | KMOSLC6A4SLC6A3 | |
| SCHEMBL728113 | 0.81 | KMO (1.00) | KMOSLC6A4SLC6A3 | |
| SCHEMBL3670421 | 0.81 | KMO (1.00) | KMOSLC6A4SLC6A3 | |
| SCHEMBL11146096 | 0.79 | MAPT (0.57) | KDM4EALDH1A1MAPT | |
| SCHEMBL7905591 | 0.78 | KMO (0.48) | KMOSLC6A4SLC6A3HPGD | |
| SCHEMBL14577821 | 0.78 | ADRB2 (0.52) | HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL7403249 | 0.77 | KMO (0.74) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323240-B1 | HALOGENATED DERIVATIVES AS ENZYME INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-11-27 | — | — | US | disclosed |