Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233101 | 0.93 | CYP1A2 (0.62) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27535389 | 0.91 | NAAA (0.58) | KMT2AMAPTMEN1ALDH1A1TDP1 | |
| SCHEMBL3490174 | 0.81 | ERAP1 (0.38) | KMT2AMAPTMEN1ALDH1A1TDP1 | |
| SCHEMBL22076496 | 0.81 | MAPT (0.67) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL5409417 | 0.80 | PSMB8 (0.41) | ALDH1A1GAAPOLBRAB9A | |
| SCHEMBL21664524 | 0.79 | CDYL (0.49) | TDP1CYP1A2 | |
| SCHEMBL1520024 | 0.78 | MAPT (0.64) | KMT2AMAPTMEN1ALDH1A1GAA | |
| Methyl 3-(3-Indolylmethyl)Propanoate SCHEMBL290808 | 0.78 | MAPT (0.71) | KMT2AMAPTMEN1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9332209 | 0.77 | MAPT (0.63) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL8123708 | 0.77 | MAPT (0.61) | KMT2AMAPTMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10513520-B2 | Sulfamide and sulfamate inhibitors of hHint1 | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-12-24 | — | — | US | disclosed |
| US-10513520-B2 | Sulfamide and sulfamate inhibitors of hHint1 | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-12-24 | — | — | US | disclosed |
| US-20180065965-A1 | SULFAMIDE AND SULFAMATE INHIBITORS OF hHint1 | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-03-08 | — | — | US | disclosed |
| US-20180065965-A1 | SULFAMIDE AND SULFAMATE INHIBITORS OF hHint1 | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-03-08 | — | — | US | disclosed |
| US-20180065965-A1 | SULFAMIDE AND SULFAMATE INHIBITORS OF hHint1 | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-03-08 | — | — | US | disclosed |
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001055107-A2 | AROMATIC AMINES AND AMIDES ACTING ON THE MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10513520-B2 | Sulfamide and sulfamate inhibitors of hHint1 | GRIN1, OPRL1, GRIN3A | KMT2A 395/4885MAPT 4226/4885MEN1 3985/4885 |
| US-20180065965-A1 | SULFAMIDE AND SULFAMATE INHIBITORS OF hHint1 | GRIN1, GRIA1, GRIN2A | KMT2A 367/4885MAPT 3101/4885MEN1 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.