Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148296 | 0.86 | AKR1B1 (0.50) | HRH3AKR1B1ALDH1A1POLBMPO | |
| SCHEMBL7519035 | 0.84 | PSMB8 (0.43) | PSMB8PSMB5HRH3NPC1RAB9A | |
| SCHEMBL21664524 | 0.82 | CDYL (0.49) | PSMB8PSMB5 | |
| SCHEMBL436079 | 0.80 | TDP1 (0.54) | PSMB8PSMB5NPC1PKMALDH1A1 | |
| SCHEMBL7869140 | 0.80 | KMT2A (0.56) | RAB9AALDH1A1POLBGAA | |
| SCHEMBL19658180 | 0.79 | KMT2A (0.41) | PSMB8PSMB5PKMRAB9AAKR1B1 | |
| SCHEMBL19658184 | 0.78 | TDP1 (0.42) | PSMB8PSMB5CYP4F2CYP4A11HRH3 | |
| SCHEMBL11032205 | 0.78 | GSK3A (0.43) | PSMB8PSMB5CYP4F2CYP4A11PKM | |
| SCHEMBL28473571 | 0.77 | HRH3 (0.50) | CYP4F2CYP4A11HRH3NPC1PKM | |
| SCHEMBL3490174 | 0.76 | ERAP1 (0.38) | PSMB8PSMB5ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217575-B2 | Avidin derivatives and uses thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2007-05-15 | — | — | US | disclosed |
| US-20040191832-A1 | Avidin derivatives and uses thereof | YEDA RESEARCH AND DEVELOPMENT CO., LTD. | 2004-09-30 | — | — | US | disclosed |
| US-20040067229-A1 | Azobenzene derivatives as labeling agents and intermediates thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2004-04-08 | — | — | US | disclosed |
| US-20040043427-A1 | Molecular bioswitch for detecting protein interactions using electrical conductivity | Knobbe, Martens, Olson & Bear, LLP | 2004-03-04 | — | — | US | disclosed |
| US-6632929-B1 | Conjugate with 4'-hydroxyazobenzene-2-carboxylic acid derivative; change from red to yellow upon binding biotin | YEDA RESEARCH AND DEVELOPMENT CO. LTD (IL) | 2003-10-14 | — | — | US | disclosed |
| US-6602987-B1 | 4'-hydroxyazobenzene-2-carboxylic acid (HABA) compounds; useful as reagents for labeling, isolation and detection of biological molecules | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2003-08-05 | — | — | US | disclosed |
| WO-2000027814-A1 | AVIDIN DERIVATIVES AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2000-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067229-A1 | Azobenzene derivatives as labeling agents and intermediates thereof | CBR1, CBR3, HBB | PSMB8 2382/4885PSMB5 3129/4885CYP4F2 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.