Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 7/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874245 | 0.93 | STAT3 (0.48) | FNTAFNTBPTGESTAS2R14STAT3 | |
| SCHEMBL7862520 | 0.91 | MMP3 (0.46) | FNTAFNTBPTGESTAS2R14MEN1 | |
| SCHEMBL7862505 | 0.89 | STAT3 (0.48) | FNTAFNTBPTGESKMT2ASTAT3 | |
| SCHEMBL7862401 | 0.89 | FNTA (0.46) | FNTAFNTBPTGESTAS2R14STAT3 | |
| SCHEMBL6624385 | 0.84 | FNTA (0.69) | FNTAFNTB | |
| SCHEMBL7869174 | 0.84 | MMP3 (0.45) | FNTAFNTBPTGESTAS2R14STAT3 | |
| SCHEMBL7869137 | 0.83 | FNTA (0.51) | FNTAFNTB | |
| SCHEMBL7862519 | 0.83 | MMP3 (0.54) | FNTAFNTBPTGESTAS2R14MMP3 | |
| SCHEMBL7862459 | 0.82 | FNTA (0.48) | FNTAFNTBPTGESTAS2R14STAT3 | |
| SCHEMBL6623598 | 0.82 | FNTA (0.60) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |