SCHEMBL78692

SCHEMBL78692

CC(C)(C)OC(=O)C(NCC(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
ITGA4 P13612 1/20 0.33
ITGB7 P26010 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA7 P43166 2/20 0.32
EGLN1 Q9GZT9 2/20 0.32
DGAT1 O75907 1/20 0.31
SYK P43405 1/20 0.31
CTSS P25774 2/20 0.30
CTSK P43235 2/20 0.30
CA12 O43570 2/20 0.30
CA14 Q9ULX7 2/20 0.30
APLNR P35414 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP2D6 P10635 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3183887 0.92 MEN1 (0.36) MEN1GAAKMT2AITGA4ITGB7
SCHEMBL3657314 0.87 CA12 (0.35) MEN1GAAKMT2AITGA4ITGB7
SCHEMBL2139561 0.83 MEN1 (0.39) MEN1GAAKMT2AITGA4ITGB7
SCHEMBL9955219 0.83
SCHEMBL2139570 0.79 CA12 (0.37) MEN1GAAKMT2AITGA4ITGB7
SCHEMBL6901600 0.79 CA12 (0.37) MEN1GAAKMT2AITGA4ITGB7
SCHEMBL68202 0.78 CA1 (0.35) MEN1GAAKMT2AITGA4ITGB7
SCHEMBL7898636 0.76 CTSK (0.42) MEN1GAAKMT2AITGA4ITGB7
SCHEMBL2137962 0.76 CTSK (0.42) MEN1GAAKMT2AITGA4ITGB7
SCHEMBL1583222 0.76 KMT2A (0.38) MEN1GAAKMT2AITGA4ITGB7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509502-B2 Hybrid immunoglobulin containing nonpeptidyl linkage BIOMOLECULAR HOLDINGS LLC (US) 2025-12-30 US disclosed
US-20250270163-A1 BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDES AND PROTEIN CONJUGATES THEREOF REGENERON PHARMA (US) 2025-08-28 US disclosed
US-12338199-B2 Bis-octahydrophenanthrene carboxamides and protein conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-06-24 US disclosed
CN-118384290-A Hybrid immunoglobulins containing non-peptide linkages 生物分子控股有限责任公司 2024-07-26 CN disclosed
WO-2024100552-A1 PRODRUGS AND COMPOSITIONS FOR OPHTHALMOLOGY APPLICATIONS ALCON INC. (CH) 2024-05-16 WO disclosed
EP-4169944-A1 PROCESS FOR PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Biomolecular Holdings LLC (US) 2023-04-26 EP disclosed
US-20220275108-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2022-09-01 US disclosed
EP-4039281-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Biomolecular Holdings LLC (US) 2022-08-10 EP disclosed
EP-3701971-B1 COMPOUNDS USEFUL IN PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2022-07-06 EP disclosed
US-20220112158-A1 BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDES AND PROTEIN CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2022-04-14 US disclosed
WO-2004035576-A2 PRE-ORGANIZED TRICYCLIC INTEGRASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2004-04-29 WO disclosed
WO-2004021996-A2 BACKBONE-SUBSTITUTED BIFUNCTIONAL DOTA LIGANDS, COMPLEXES AND COMPOSITIONS THEREOF, AND METHODS OF USING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2004-03-18 WO disclosed
CN-1434822-A Substituted oxazolidinones and their use in the field of blood coagulation BAYER AG (DE) 2003-08-06 CN disclosed
US-20020048774-A1 Liquid phase parallel synthesis of chemical libraries BRISTOL-MYERS SQUIBB PHARMA RESEARCH LABS, INC. 2002-04-25 US disclosed
US-6245937-B1 COMBINATORIAL LIBRARIES OF CHEMICAL COMPOUNDS SYNTHESIZED BY BIPHASIC SYNTHESIS UTILIZING SPECIFIED TEMPLATES DUPONT PHARMACEUTICALS RESEARCH LABORATORIES, INC. 2001-06-12 US disclosed
WO-2000059896-A1 225Ac-HEHA AND RELATED COMPOUNDS, METHODS OF SYNTHESIS AND METHODS OF USE THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2000-10-12 WO disclosed
EP-0503301-B1 Peptide derivatives and application thereof FUJI PHOTO FILM CO LTD (JP) 1997-11-26 EP disclosed
US-5436221-A Oligopeptides as antitumor agents FUJI PHOTO FILM CO., LTD. (JP) 1995-07-25 US disclosed
EP-0619118-A1 Use of peptide derivatives FUJI PHOTO FILM CO., LTD. (JP) 1994-10-12 EP disclosed
EP-0503301-A2 Peptide derivatives and application thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220275108-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE FCGR3B, FCGR2A, VSIG8 MEN1 4505/4885GAA 4742/4885KMT2A 2199/4885
US-12338199-B2 Bis-octahydrophenanthrene carboxamides and protein conjugates thereof NR1H4, NR1H3, OGFR MEN1 4763/4885GAA 2178/4885KMT2A 2525/4885
US-20020048774-A1 Liquid phase parallel synthesis of chemical libraries CDK2, CDC25C, POLR2H MEN1 3009/4885GAA 4044/4885KMT2A 1893/4885
US-20220112158-A1 BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDES AND PROTEIN CONJUGATES THEREOF NR1H4, NR1H3, OGFR MEN1 4763/4885GAA 2178/4885KMT2A 2525/4885
US-20250270163-A1 BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDES AND PROTEIN CONJUGATES THEREOF NR1H4, NR1H3, OGFR MEN1 4763/4885GAA 2178/4885KMT2A 2525/4885
US-12509502-B2 Hybrid immunoglobulin containing nonpeptidyl linkage FCGR2A, FCGR3B, CD74 MEN1 3731/4885GAA 4768/4885KMT2A 3327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.