SCHEMBL7869260

SCHEMBL7869260

CCCCO[Si](OCCCC)(OCCCC)c1cccc(S(=O)(=O)N=[N+]=[N-])c1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 2/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
KAT6A Q92794 1/20 0.31
ABCC1 P33527 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7628576 0.93
SCHEMBL7877836 0.89 ABCB1 (0.34) ABCB1TSHRALDH1A1CA12CA1
SCHEMBL7627611 0.87 F2 (0.30)
SCHEMBL7877837 0.86 TSHR (0.38) ABCB1TSHRALDH1A1CA12CA1
SCHEMBL7631034 0.81
SCHEMBL7869254 0.80 F2 (0.35)
SCHEMBL7628196 0.78 CA1 (0.33) TSHRALDH1A1CA12CA1CA2
SCHEMBL7622816 0.76 TSHR (0.36) ABCB1TSHRCA12CA1CA2
SCHEMBL975609 0.75 LTA4H (0.37) TSHR
SCHEMBL7877834 0.74 TRPV1 (0.32) TSHRALDH1A1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6331597-B1 Azidosilane-modified, moisture-curable polyolefin polymers, process for making, and articles obtained therefrom THE DOW CHEMICAL COMPANY 2001-12-18 US disclosed