Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878816 | 0.86 | PDE10A (0.36) | MAPK1DPP4ALDH1A1 | |
| SCHEMBL7880330 | 0.84 | DPP4 (0.36) | MAPK1AOC3DPP4KDM4EMAPT | |
| SCHEMBL7882810 | 0.80 | NPSR1 (0.31) | — | |
| SCHEMBL2068182 | 0.79 | GRM5 (0.42) | MAPK1AOC3DPP4KDM4EMAPT | |
| SCHEMBL7870161 | 0.74 | PIK3C3 (0.40) | MAPK1AOC3KDM4EMAPTLMNA | |
| SCHEMBL7871957 | 0.68 | DPP4 (0.36) | MAPK1DPP4ALDH1A1 | |
| SCHEMBL2068252 | 0.67 | MAPK1 (0.32) | MAPK1AOC3 | |
| SCHEMBL14486055 | 0.66 | EGFR (0.32) | — | |
| SCHEMBL18059421 | 0.65 | LMNA (0.34) | KDM4ELMNA | |
| SCHEMBL7878857 | 0.64 | DPP4 (0.34) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139747-A1 | 1H-IMIDAZO[4, 5-c]QUINOLINONE COMPOUNDS, USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2010-12-09 | — | — | WO | disclosed |