Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2067188 | 0.82 | NPC1 (0.37) | DPP4SMN1; SMN2ALDH1A1TNKS2 | |
| SCHEMBL7878816 | 0.80 | PDE10A (0.36) | DPP4ALDH1A1MAPK1 | |
| SCHEMBL2068556 | 0.73 | DGAT1 (0.41) | DPP4SMN1; SMN2RXFP1 | |
| SCHEMBL9688618 | 0.73 | AGXT (0.45) | DPP4SMN1; SMN2ALDH1A1RXFP1 | |
| SCHEMBL9686722 | 0.70 | SMN1; SMN2 (0.40) | DPP4SMN1; SMN2ALDH1A1TNKS2RXFP1 | |
| SCHEMBL15270708 | 0.70 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL13496376 | 0.69 | CA12 (0.39) | ALDH1A1MAPK1 | |
| SCHEMBL7877008 | 0.68 | — | — | |
| SCHEMBL3393653 | 0.68 | AGBL2 (0.39) | ALDH1A1 | |
| SCHEMBL7869375 | 0.68 | MAPK1 (0.34) | DPP4ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139747-A1 | 1H-IMIDAZO[4, 5-c]QUINOLINONE COMPOUNDS, USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2010-12-09 | — | — | WO | disclosed |