Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385240 | 0.86 | DRD1 (0.37) | MEN1KMT2ADRD1 | |
| SCHEMBL9586997 | 0.85 | DRD1 (0.46) | MEN1KMT2ADRD1POLB | |
| SCHEMBL9333186 | 0.84 | DRD1 (0.51) | DRD1 | |
| SCHEMBL7497691 | 0.83 | POLB (0.56) | MEN1KMT2ADRD1MAPTPOLB | |
| SCHEMBL7869540 | 0.79 | MEN1 (0.46) | MEN1KMT2ADRD1MAPTATM | |
| SCHEMBL8329396 | 0.79 | MEN1 (0.46) | MEN1KMT2ADRD1MAPT | |
| SCHEMBL9384977 | 0.79 | HSD17B10 (0.49) | MEN1KMT2ADRD1 | |
| SCHEMBL7505146 | 0.79 | HSD17B10 (0.59) | MEN1KMT2ADRD1MAPTPOLB | |
| SCHEMBL9525676 | 0.78 | HSD17B10 (0.48) | MEN1KMT2ADRD1 | |
| SCHEMBL9523968 | 0.78 | HSD17B10 (0.48) | MEN1KMT2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306853-B1 | DICARBOXYLIC ESTER DERIVATIVES OF DIHYDROPYRIDINE COMPOUNDS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-1055672-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 2000-11-29 | — | — | EP | disclosed |
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | disclosed |
| EP-0466711-B1 | DIHYDROPYRIMIDINE ANTIALLERGY AGENTS | PFIZER LTD (GB) | 1993-10-27 | — | — | EP | disclosed |
| US-5250531-A | Antiallergens, antiinflammatory agents | PFIZER INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-5248681-A | DIHYDROPYRIDINE ANTIALLERGY AGENTS | PFIZER INC. (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| US-5149814-A | Alkyl 2-benzylidene-4-(2-alkylimidazopyrid-1-yl) benzoylacetate esters as intermediate compounds | PFIZER INC (US) | 1992-09-22 | — | — | US | disclosed |
| US-5120747-A | Antiallergens, antiinflammatory agent | PFIZER INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0467895-A1 | DIHYDROPYRIDINE ANTIALLERGY AGENTS | Pfizer Limited (GB) | 1992-01-29 | — | — | EP | disclosed |
| EP-0466711-A1 | DIHYDROPYRIMIDINE ANTIALLERGY AGENTS. | PFIZER LTD (GB) | 1992-01-22 | — | — | EP | disclosed |
| US-5070205-A | Chemical intermediate for anticoagulants | PFIZER INC. (US) | 1991-12-03 | — | — | US | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |
| EP-0310386-B1 | 4-ARYL-5-CARBAMOYL-1,4-DIHYDROPYRIDINES | Pfizer Limited (GB) | 1991-11-06 | — | — | EP | disclosed |
| US-5063237-A | Antiallergens and antiinflammatory agents | PFIZER INC. (US) | 1991-11-05 | — | — | US | disclosed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | disclosed |
| WO-1990012015-A1 | DIHYDROPYRIDINE ANTIALLERGY AGENTS | PFIZER LIMITED (GB) | 1990-10-18 | — | — | WO | disclosed |
| WO-1990011281-A1 | DIHYDROPYRIMIDINE ANTIALLERGY AGENTS | PFIZER LIMITED (GB) | 1990-10-04 | — | — | WO | disclosed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | disclosed |
| US-4935430-A | Platelet activating factor antagonists | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |