Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494726 | 0.90 | ADRA2A (0.44) | ALOX15MEN1KMT2ALMNAKDM4E | |
| Hydrochloric Acid SCHEMBL7869767 | 0.89 | ADRA2A (0.44) | ALOX15MEN1KMT2ALMNAKDM4E | |
| SCHEMBL7873099 | 0.86 | PARP1 (0.45) | KDM4EPRKAA2PARP1ALDH1A1PRMT5 | |
| SCHEMBL7869108 | 0.86 | PRMT5 (0.46) | MEN1KMT2ANAMPTPRKAA2PARP1 | |
| SCHEMBL8495364 | 0.85 | ALOX15 (0.47) | ALOX15MEN1KMT2ALMNAKDM4E | |
| SCHEMBL7868154 | 0.85 | PARP1 (0.46) | KDM4EPRKAA2PARP1ALDH1A1L3MBTL1 | |
| SCHEMBL7873041 | 0.85 | PARP1 (0.42) | KDM4ENAMPTPRKAA2PARP1PRMT5 | |
| Hydrochloric Acid SCHEMBL7866438 | 0.85 | ALOX15 (0.46) | ALOX15MEN1KMT2ALMNAKDM4E | |
| SCHEMBL8491991 | 0.84 | PARP1 (0.42) | KDM4ENAMPTPRKAA2PARP1ALDH1A1 | |
| SCHEMBL7873097 | 0.84 | GAA (0.45) | KDM4EPRKAA2PARP1ALDH1A1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306860-B1 | ANTIVIRAL ACTIVITIES AGAINST HEPATATIS B AS WELL AS HUMAN IMMUNODEFICIENCY VIRUS | DONG WHA PHARM. INC. CO., LTD. (KR) | 2001-10-23 | — | — | US | disclosed |
| WO-1999058526-A1 | NOVEL 2,5-PYRIDINEDICARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-11-18 | — | — | WO | disclosed |