Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7874146 | 0.99 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7869909 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRMAPTTP53MCHR1 | |
| Hydrochloric Acid SCHEMBL7869929 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2TSHRMAPTTP53MCHR1 | |
| Hydrochloric Acid SCHEMBL7874098 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7866910 | 0.85 | ALDH1A1 (0.49) | SMN1; SMN2TSHRMAPTTP53MCHR1 | |
| SCHEMBL7866953 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2TSHRMAPTTP53RAB9A | |
| Hydrochloric Acid SCHEMBL7862199 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2TSHRMAPTTP53RAB9A | |
| SCHEMBL7866950 | 0.81 | LMNA (0.48) | SMN1; SMN2TSHRMAPTMCHR1KDM4E | |
| Hydrochloric Acid SCHEMBL7874134 | 0.80 | LMNA (0.47) | SMN1; SMN2TSHRMAPTMCHR1KDM4E | |
| Hydrochloric Acid SCHEMBL7862092 | 0.79 | MAPT (0.53) | SMN1; SMN2TSHRTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |