Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7874134 | 0.99 | LMNA (0.47) | LMNAKMT2AMEN1MAPTMCHR1 | |
| SCHEMBL8003660 | 0.88 | NPSR1 (0.50) | LMNAMAPTMCHR1RAB9ASMN1; SMN2 | |
| SCHEMBL7866971 | 0.84 | ALDH1A1 (0.45) | LMNAKMT2AMEN1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL7866984 | 0.83 | ALDH1A1 (0.44) | LMNAKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7869922 | 0.82 | MAPT (0.56) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL7869917 | 0.81 | SMN1; SMN2 (0.50) | LMNAKMT2AMAPTMCHR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7868840 | 0.81 | MAPT (0.55) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL7874146 | 0.80 | SMN1; SMN2 (0.49) | LMNAKMT2AMAPTMCHR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7870706 | 0.77 | MCHR1 (0.48) | KMT2AMEN1MAPTMCHR1ALDH1A1 | |
| SCHEMBL7862182 | 0.77 | NPC1 (0.46) | LMNAKMT2AMEN1MAPTMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |