Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7866916 | 0.98 | MEN1 (0.63) | MEN1KMT2ACYP1A2ADRB2ADRB1 | |
| SCHEMBL11111056 | 0.84 | ALDH1A1 (0.80) | MEN1KMT2ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL10802880 | 0.82 | ALDH1A1 (0.77) | MEN1KMT2ACYP1A2ALDH1A1LMNA | |
| SCHEMBL7869922 | 0.82 | MAPT (0.56) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10409422 | 0.81 | L3MBTL1 (0.64) | ADRB2ALOX15TSHRALDH1A1LMNA | |
| SCHEMBL7866908 | 0.81 | MAPT (0.50) | MEN1KMT2ACYP1A2ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL7868840 | 0.81 | MAPT (0.55) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9570672 | 0.80 | ALDH1A1 (0.75) | MEN1KMT2ACYP1A2ALDH1A1LMNA | |
| SCHEMBL9570550 | 0.80 | ALDH1A1 (0.75) | MEN1KMT2ACYP1A2ALDH1A1LMNA | |
| SCHEMBL7873989 | 0.80 | SMN1; SMN2 (0.47) | MEN1KMT2ACYP1A2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |