SCHEMBL7869958

SCHEMBL7869958

Nc1c(F)c(F)c(C(=O)c2c(F)c(N)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
HTT P42858 2/20 0.33
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
MAPK1 P28482 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869990 1.00 CES2 (0.36) CES2CES1HTTLMNATP53
SCHEMBL7869943 0.95 CES2 (0.33) CES2CES1HTT
SCHEMBL27471473 0.87 CES2 (0.34) CES2CES1HTTLMNATP53
SCHEMBL661258 0.83 CES2 (0.46) CES2CES1HTTLMNATP53
SCHEMBL19131132 0.82 KMT2A (0.35) CES2CES1HTTLMNATP53
SCHEMBL8464805 0.79 KMT2A (0.32) CES2CES1GAA
SCHEMBL3145740 0.76 POLB (0.35) CES2CES1HTT
SCHEMBL506102 0.76 KMT2A (0.33) CES2CES1HTTMAPK1GAA
SCHEMBL20853606 0.76 CES2 (0.32) CES2CES1HTT
SCHEMBL6124196 0.74 CES2 (0.36) CES2CES1HTTLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303743-B1 Polyimide for optical communications, method of preparing the same, and method of forming multiple polyimide film using the polyimide SAMSUNG ELECTRONICS CO., LTD. (KR) 2001-10-16 US disclosed
US-6115514-A FILM THICKNESS OF POLYIMIDE FILM FORMED BY THERMALLY IMIDIZING A POLYAMIC ACID IS SET AT NOT MORE THAN 20 MICROMETERS; HUMIDITY RESISTANCE, STRENGTH, FLEXIBILITY NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2000-09-05 US disclosed
US-6100371-A Polyimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-08-08 US disclosed
US-6077928-A Bis(dialkylmaleimide) derivative and polyetherimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-06-20 US disclosed
US-6072920-A Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2000-06-06 US disclosed
US-6048986-A DEHYDRATION OF DIFLUOROPYROMELLITIC ACID TO FORM DIFLUOROPYROMELLITIC DIANHYDRIDE NIPPON TELEGRAPH AND TELEPHONE CORP. (JP) 2000-04-11 US disclosed
US-6031061-A Bis (triaklyltrimellitic anhydride) derivative and polyesterimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-02-29 US disclosed
US-6028159-A Polyamideimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-02-22 US disclosed
US-6013759-A Polyamideimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-01-11 US disclosed
EP-0623830-B1 Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH & TELEPHONE (JP) 1999-08-18 EP disclosed
US-5901259-A Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1999-05-04 US disclosed
US-5849934-A Method for preparing aromatic compounds NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1998-12-15 US disclosed
US-5750731-A POLYIMIDE ANHYDRIDE MONOMERS NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) 1998-05-12 US disclosed
US-5694496-A WAVEGUIDE COMPRISING AN AROMATIC FLUORO-POLYIMIDE; HEAT RESISTANCE, FLEXIBILITY, WATERPROOFING, STRENGTH NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1997-12-02 US disclosed
EP-0480266-B1 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH & TELEPHONE (JP) 1996-06-26 EP disclosed
US-5449741-A Electronics with impact strength NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1995-09-12 US disclosed
EP-0623830-A1 Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-11-09 EP disclosed
US-5233018-A Heat resistance and low optical transmission loss in the near-infrared region; integrated circuits NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1993-08-03 US disclosed
EP-0480266-A2 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-15 EP disclosed