SCHEMBL506102

SCHEMBL506102

Nc1c(F)c(F)c(C(=O)O)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.33
MEN1 O00255 5/20 0.33
KDM4E B2RXH2 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
KEAP1 Q14145 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
CYP1A2 P05177 1/20 0.32
GAA P10253 1/20 0.31
ASPH Q12797 1/20 0.31
KDM8 Q8N371 1/20 0.31
DHODH Q02127 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19131132 0.95 KMT2A (0.35) KMT2AMEN1KDM4ESMN1; SMN2CRHBP
SCHEMBL8464805 0.92 KMT2A (0.32) KMT2AMEN1KDM4ESMN1; SMN2CRHBP
SCHEMBL6036813 0.86 KMT2A (0.36) KMT2AMEN1KDM4ESMN1; SMN2CRHBP
SCHEMBL30366477 0.86 KMT2A (0.36) KMT2AMEN1KDM4ESMN1; SMN2CRHBP
SCHEMBL141037 0.85 CYP1A2 (0.40) KMT2AMEN1KDM4ESMN1; SMN2CRHBP
SCHEMBL12548792 0.84 KMT2A (0.36) KMT2AMEN1KDM4ESMN1; SMN2CRHBP
Hydroxyamine SCHEMBL31050881 0.82 CES2 (0.40) KMT2AMEN1KDM4ESMN1; SMN2CRHBP
Fluoride SCHEMBL2393600 0.82 CYP1A2 (0.38) KMT2AMEN1KDM4ESMN1; SMN2CRHBP
Hydrochloric Acid SCHEMBL7881715 0.82 CYP1A2 (0.38) KMT2AMEN1KDM4ESMN1; SMN2CRHBP
Hydrochloric Acid SCHEMBL4414501 0.82 CYP1A2 (0.38) KMT2AMEN1KDM4ESMN1; SMN2CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2025-07-01 US claimed
CN-114497378-B Broadband near-infrared photoelectric detector with 4-amino-2, 3,5, 6-tetrafluorobenzoic acid as dopant and preparation method thereof 吉林大学 2025-05-30 CN claimed
CN-115746069-B Compound for activating and releasing drug molecules in response to X-rays and synthesis method thereof 中科帅天医药(深圳)有限公司 2024-06-18 CN claimed
WO-2024108687-A1 MITOMYCIN C PRODRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳先进技术研究院 2024-05-30 WO claimed
CN-115850288-A Mitomycin C prodrug and preparation method and application thereof 深圳先进技术研究院 2023-03-28 CN claimed
CN-115746069-A Compound for activating and releasing drug molecules in response to X-rays and synthetic method thereof 中科帅天医药(深圳)有限公司 2023-03-07 CN claimed
CN-114497378-A Broadband near-infrared photoelectric detector using 4-amino-2,3,5,6-tetrafluorobenzoic acid as dopant and preparation method thereof 吉林大学 2022-05-13 CN claimed
CN-113604194-A Modified epoxy resin binder for stone and preparation method thereof 湖南柯盛新材料有限公司 2021-11-05 CN claimed
CN-113583606-A Stone binder of polyphenyl ether modified epoxy resin and preparation method thereof 湖南柯盛新材料有限公司 2021-11-02 CN claimed
CN-113528068-A Double-component stone crack sealer and preparation method thereof 湖南柯盛新材料有限公司 2021-10-22 CN claimed
US-20080069968-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-03-20 US claimed
EP-1799791-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2007-06-27 EP claimed
US-7109365-B2 Processes for solubilizing organometallic compounds in fluorinated solvents by addition of a partly fluorinated non-catalytic co-solubilizer XEROX CORPORATION (US) 2006-09-19 US claimed
WO-2006039824-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2006-04-20 WO claimed
US-7006780-B2 Partially fluorinated polymer coated development electrodes XEROX CORPORATION (US) 2006-02-28 US claimed
US-20050113244-A1 Processes for solubilizing organometallic compounds in fluorinated solvents by addition of a partly fluorinated non-catalytic co-solubilizer XEROX CORPORATION 2005-05-26 US claimed
US-20050111884-A1 Partially fluorinated polymer coated development electrodes XEROX CORPORATION 2005-05-26 US claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113244-A1 Processes for solubilizing organometallic compounds in fluorinated solvents by addition of a partly fluorinated non-catalytic co-solubilizer NAF1, PFAS, AFF2 KMT2A 1355/4885MEN1 625/4885KDM4E 2625/4885
US-20080069968-A1 Photocrosslinkable Materials PARG, VSIR, IGLV6-57 KMT2A 558/4885MEN1 3530/4885KDM4E 844/4885
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture NOS1, NOS3, NOS2 KMT2A 4254/4885MEN1 4081/4885KDM4E 4548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.