Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511575 | 0.89 | POLB (0.50) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL31453818 | 0.89 | POLB (0.50) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL17332189 | 0.81 | POLB (0.43) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL106105 | 0.72 | POLB (0.65) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL11395195 | 0.72 | POLB (0.36) | POLBTDP1 | |
| SCHEMBL5494856 | 0.71 | POLB (0.48) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL15645293 | 0.71 | POLB (0.48) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL15645762 | 0.71 | POLB (0.48) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL15645760 | 0.71 | POLB (0.48) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL4344019 | 0.70 | POLB (0.35) | POLBTDP1CTDSP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303744-B1 | NOVEL DICARBOXYLIC ENDCAP SUCH AS 7-HYDROXY-5-NORBORNENE-2,3-DICARBOXYLIC ANHYDRIDE AND 7,7-DIFLOURO-5-NORBORNENE-2,3-DICARBOXYLIC ANHYDRIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION | 2001-10-16 | — | — | US | claimed |
| US-6303744-B1 | NOVEL DICARBOXYLIC ENDCAP SUCH AS 7-HYDROXY-5-NORBORNENE-2,3-DICARBOXYLIC ANHYDRIDE AND 7,7-DIFLOURO-5-NORBORNENE-2,3-DICARBOXYLIC ANHYDRIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION | 2001-10-16 | — | — | US | disclosed |
| US-6274699-B1 | ENDCAPPING WITH A ISOBENZOFURAN COMPOUND | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION | 2001-08-14 | — | — | US | disclosed |