SCHEMBL7870136

SCHEMBL7870136

N#Cc1c(F)c(Sc2ccc(F)cc2)c(Sc2ccc(F)cc2)c(F)c1C#N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
MAOA P21397 5/20 0.40
MAOB P27338 5/20 0.40
PTGS2 P35354 1/20 0.39
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
CYP3A4 P08684 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
POLB P06746 1/20 0.36
MAP2K2 P36507 1/20 0.35
MAP2K1 Q02750 1/20 0.35
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7873517 0.85 MAOA (0.53) CYP1A2NPSR1MAOAMAOBKMT2A
SCHEMBL7870102 0.85 L3MBTL1 (0.42) CYP1A2NPSR1MAOAMAOBKMT2A
SCHEMBL7106251 0.84 MAOA (0.48) CYP1A2NPSR1MAOAMAOBKMT2A
SCHEMBL7869250 0.77 CA12 (0.49) CYP1A2NPSR1MAOAMAOBKMT2A
SCHEMBL7938298 0.72 MAOB (0.65) CYP1A2NPSR1MAOAMAOBKMT2A
SCHEMBL15535583 0.72 CYP1A2 (0.40) CYP1A2NPSR1MAOAMAOBPTGS2
SCHEMBL7870119 0.72 L3MBTL1 (0.43) NPSR1MAOAMAOBKMT2AMEN1
SCHEMBL2455103 0.71 MAOA (0.37) CYP1A2NPSR1MAOAMAOBKMT2A
SCHEMBL2453615 0.71 ADORA1 (0.37) NPSR1MAOAMAOBKMT2AMEN1
SCHEMBL576260 0.69 MEN1 (0.48) CYP1A2NPSR1KMT2AMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882768-B1 Method for producing of phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2001-12-19 EP disclosed
US-6034236-A REACTING A PHTHALONITRILE WITH A METAL OXIDE IN PRESENCE OF A SULFONIC ACID CATALYST NIPPON SHOKUBAI CO., LTD. (JP) 2000-03-07 US disclosed
EP-0882768-A2 Method for producing of phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-09 EP disclosed