Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865873 | 0.78 | AR (0.37) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL31121358 | 0.78 | AR (0.37) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL7864635 | 0.75 | AR (0.37) | THRBCYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL7865948 | 0.75 | PDE5A (0.45) | SMN1; SMN2ALDH1A1NFE2L2MAPK1NPC1 | |
| SCHEMBL12336197 | 0.72 | SMN1; SMN2 (0.38) | CYP1A2CYP3A4CYP2C9SMN1; SMN2ALDH1A1 | |
| SCHEMBL911419 | 0.70 | CCR4 (0.43) | KMT2ANFE2L2MAPK1NPC1RAB9A | |
| SCHEMBL31212206 | 0.69 | TLR8 (0.39) | SMN1; SMN2ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL439658 | 0.69 | NFE2L2 (0.36) | ALDH1A1KMT2ANFE2L2MAPK1NPC1 | |
| SCHEMBL5942168 | 0.67 | HPGD (0.40) | SMN1; SMN2KMT2ANFE2L2MAPK1NPC1 | |
| SCHEMBL911553 | 0.67 | DYRK1A (0.41) | KMT2ANFE2L2MAPK1MAPTAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303814-B1 | N-[1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides | DOW AGROSCIENCES LLC | 2001-10-16 | — | — | US | disclosed |
| EP-0877745-B1 | N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-25 | — | — | EP | disclosed |