Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870542 | 0.75 | THRB (0.33) | ARMAPTL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL31563751 | 0.73 | AR (0.38) | ARKMT2AAPLNRKDM4E | |
| SCHEMBL22165527 | 0.73 | AR (0.38) | ARKMT2AAPLNRKDM4E | |
| SCHEMBL1536311 | 0.72 | CYP3A4 (0.36) | MAPTL3MBTL1TDP1CYP1A2CYP2C9 | |
| SCHEMBL1662248 | 0.69 | DYRK1A (0.40) | MAPTL3MBTL1KMT2AALDH1A1MAPK1 | |
| SCHEMBL30320423 | 0.69 | DYRK1A (0.40) | MAPTL3MBTL1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8351800 | 0.68 | LMNA (0.37) | MAPTLMNAMAPK1CYP3A4 | |
| SCHEMBL1536323 | 0.68 | LMNA (0.37) | MAPTLMNAKDM4EMAPK1CYP3A4 | |
| SCHEMBL4073435 | 0.67 | DOT1L (0.39) | MAPTL3MBTL1KMT2AALDH1A1POLB | |
| SCHEMBL1445758 | 0.67 | PKM (0.40) | MAPTL3MBTL1TDP1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877745-B1 | N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-25 | — | — | EP | disclosed |