Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.54 |
| ▸ | BMP1 | P13497 | 2/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930501 | 0.90 | HDAC1 (0.60) | MMP1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL6931713 | 0.90 | HDAC1 (0.60) | MMP1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL28618738 | 0.86 | HTT (0.50) | MMP1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL7080603 | 0.84 | HTT (0.51) | MMP1MEP1BCA1CA2 | |
| SCHEMBL21946015 | 0.80 | ALDH1A1 (0.48) | HDAC1HDAC8HDAC3HDAC2HDAC10 | |
| SCHEMBL11431967 | 0.79 | HDAC1 (0.49) | MMP1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL28510612 | 0.78 | ELANE (0.38) | MMP1CA1CA2 | |
| SCHEMBL7308342 | 0.75 | MMP1 (0.46) | MMP1HDAC1HDAC8HDAC3HDAC2 | |
| Hydroxyamine SCHEMBL7655304 | 0.74 | PDE4B (0.49) | HDAC1HDAC8HDAC3HDAC2HDAC10 | |
| SCHEMBL5604356 | 0.73 | F2RL1 (0.69) | MMP1HDAC1HDAC8HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | claimed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |