Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27767605 | 0.85 | KYNU (0.65) | KYNUMMP13SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9064967 | 0.85 | KYNU (0.65) | KYNUMMP13SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7867008 | 0.84 | KYNU (0.51) | KYNUMMP13SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7867063 | 0.84 | NPC1 (0.54) | KYNUMMP13SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7869862 | 0.84 | ALDH1A1 (0.54) | KYNUMMP13SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL30423587 | 0.80 | SLC1A3 (0.52) | KYNUSLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL7868823 | 0.80 | SLC1A3 (0.52) | KYNUSLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL7183670 | 0.79 | MMP13 (0.56) | KYNUMMP13MMP1MMP2MMP9 | |
| SCHEMBL7178201 | 0.79 | MMP13 (0.75) | KYNUMMP13ALDH1A1MMP1MMP2 | |
| SCHEMBL7178204 | 0.79 | MMP13 (0.75) | KYNUMMP13ALDH1A1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |