Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12470669 | 0.91 | ALDH1A1 (0.67) | ALDH1A1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL20544603 | 0.88 | HDAC1 (0.68) | ALDH1A1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL7073415 | 0.83 | MTNR1A (0.62) | ALDH1A1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL7862221 | 0.83 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL12587 | 0.81 | MTNR1A (0.59) | ALDH1A1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL7355817 | 0.81 | MTNR1A (0.64) | ALDH1A1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL11618114 | 0.78 | RAB9A (0.57) | ALDH1A1NPC1RAB9AHDAC1HDAC8 | |
| SCHEMBL12470557 | 0.77 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL21102352 | 0.77 | MTNR1A (0.55) | ALDH1A1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL7867057 | 0.77 | NPC1 (0.59) | ALDH1A1NPC1RAB9AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | claimed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |