Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870876 | 0.92 | HSD17B10 (0.44) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4894950 | 0.87 | CYP3A4 (0.53) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3419436 | 0.85 | CYP1A2 (0.66) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30194823 | 0.82 | HSD17B10 (0.57) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10343906 | 0.81 | S100B (0.46) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6437847 | 0.80 | HSD17B10 (0.43) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11642082 | 0.80 | CYP2C19 (0.49) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11646164 | 0.80 | HSD17B10 (0.49) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29385647 | 0.79 | ALDH1A1 (0.49) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4897902 | 0.79 | ALDH1A1 (0.49) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303540-B1 | CONTAINING DIPHENYLSULFONE BRIDGEABLE TYPE COMPOUND AND SULFONAMIDE COMPOUND | NIPPON PAPER INDUSTRIES CO LTD (JP) | 2001-10-16 | — | — | US | disclosed |