Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870880 | 0.92 | HSD17B10 (0.50) | HSD17B10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4897902 | 0.88 | ALDH1A1 (0.49) | HSD17B10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29385647 | 0.88 | ALDH1A1 (0.49) | HSD17B10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30194823 | 0.87 | HSD17B10 (0.57) | HSD17B10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27449891 | 0.81 | ALDH1A1 (0.44) | HSD17B10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6259364 | 0.80 | S100B (0.43) | HSD17B10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3419436 | 0.80 | CYP1A2 (0.66) | HSD17B10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8977097 | 0.80 | S100B (0.47) | HSD17B10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1071657 | 0.79 | CES2 (0.46) | HSD17B10MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9243334 | 0.79 | CYP3A4 (0.47) | HSD17B10CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303540-B1 | CONTAINING DIPHENYLSULFONE BRIDGEABLE TYPE COMPOUND AND SULFONAMIDE COMPOUND | NIPPON PAPER INDUSTRIES CO LTD (JP) | 2001-10-16 | — | — | US | disclosed |