SCHEMBL787127

SCHEMBL787127

c1nc(C2CNCCO2)nc(N2CCNCC2)n1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.39
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HRH1 P35367 1/20 0.36
USP2 O75604 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CASP1 P29466 1/20 0.35
CASP4 P49662 1/20 0.35
CASP5 P51878 1/20 0.35
HTR1A P08908 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9681051 0.78 HTR1A (0.36) HRH1USP2SMN1; SMN2TDP1HTR1A
Hydrochloric Acid SCHEMBL28628720 0.77 HRH1 (0.38) KDM4EALDH1A1HRH1USP2SMN1; SMN2
SCHEMBL27499219 0.76
SCHEMBL28170128 0.76 DRD2 (0.37)
SCHEMBL29183999 0.75 PIK3CA (0.51)
SCHEMBL28710773 0.74 HRH1 (0.61) ADRB1KDM4EALDH1A1HRH1USP2
SCHEMBL29183810 0.73 PIK3CA (0.54)
SCHEMBL27547345 0.73 DRD2 (0.41)
SCHEMBL9730687 0.72 SMN1; SMN2 (0.50) KDM4EALDH1A1SMN1; SMN2TDP1HTR1A
SCHEMBL434846 0.71 POLB (0.55) ADRB1KDM4EALDH1A1HRH1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4216236-A2 LOW SMOKE, ZERO HALOGEN SELF-REGULATING HEATING CABLE NVENT SERVICES GMBH (CH) 2023-07-26 EP claimed
EP-3577658-B1 LOW SMOKE ZERO HALOGEN SELF-REGULATING HEATING CABLE NVENT SERVICES GMBH (CH) 2022-12-21 EP claimed
CN-110054898-B Halogen-free flame-retardant thermoplastic elastomer and preparation method and application thereof 广东省石油与精细化工研究院 2021-12-14 CN claimed
CN-110054898-A A kind of halogen-free flame-retardant thermoplastic elastomer and its preparation method and application 广东省石油与精细化工研究院 2019-07-26 CN claimed
CN-103003344-A Flame-retardant insulated electrical conductor DSM IP ASSETS BV 2013-03-27 CN claimed
US-11956865-B2 Low smoke, zero halogen self-regulating heating cable NVENT SERVICES GMBH (CH) 2024-04-09 US disclosed
US-20240032157-A1 Improving Flammability of Heating Cable CHEMELEX EUROPE GMBH (CH) 2024-01-25 US disclosed
US-11871486-B2 Low smoke, zero halogen self-regulating heating cable NVENT SERVICES GMBH (CH) 2024-01-09 US disclosed
US-11778700-B2 Flammability of heating cable NVENT SERVICES GMBH (CH) 2023-10-03 US disclosed
US-20230284344-A1 Low Smoke, Zero Halogen Self-Regulating Heating Cable CHEMELEX EUROPE GMBH (CH) 2023-09-07 US disclosed
EP-4216236-A2 LOW SMOKE, ZERO HALOGEN SELF-REGULATING HEATING CABLE NVENT SERVICES GMBH (CH) 2023-07-26 EP disclosed
EP-3577658-B1 LOW SMOKE ZERO HALOGEN SELF-REGULATING HEATING CABLE NVENT SERVICES GMBH (CH) 2022-12-21 EP disclosed
CN-103003344-B Flame-retardant insulated electrical conductor DSM IP ASSETS BV 2014-09-03 CN disclosed
US-20140011923-A1 Polytriazinyl Compounds as Flame Retardants and Light Stabilizers MCA TECHNOLOGIES GMBH (CH) 2014-01-09 US disclosed
CN-103003344-A Flame-retardant insulated electrical conductor DSM IP ASSETS BV 2013-03-27 CN disclosed
US-20120245291-A1 Polytriazinyl Compounds as Flame Retardants and Light Stabilizers MCA TECHNOLOGIES GMBH (CH) 2012-09-27 US disclosed
US-8202924-B2 Polytriazinyl compounds as flame retardants and light stabilizers MCA TECHNOLOGIES GMBH (CH) 2012-06-19 US disclosed
US-20120071594-A1 POLYTRIAZINYL COMPOUNDS AS FLAME RETARDANTS AND LIGHT STABILIZERS MCA TECHNOLOGIES GMBH (CH) 2012-03-22 US disclosed
EP-2130854-A2 Polytriazinyl compounds as flame retardants and light stabilizers MCA Technologies GMBH (CH) 2009-12-09 EP disclosed
US-20090281215-A1 Polytriazinyl Compounds as Flame Retardants and Light Stabilizers MCA TECHNOLOGIES GMBH (CH) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071594-A1 POLYTRIAZINYL COMPOUNDS AS FLAME RETARDANTS AND LIGHT STABILIZERS PCBP1, PBRM1, TAF5 ADRB1 2420/4885KDM4E 2679/4885ALDH1A1 1526/4885
US-20090281215-A1 Polytriazinyl Compounds as Flame Retardants and Light Stabilizers PSMB5, POLL, F12 ADRB1 1311/4885KDM4E 1945/4885ALDH1A1 2014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.