Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CPS1 | P31327 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878481 | 0.89 | ALDH1A1 (0.55) | HTTKDM4EALDH1A1CPS1LMNA | |
| SCHEMBL17400735 | 0.85 | CPS1 (0.50) | HTTKDM4EALDH1A1CPS1LMNA | |
| SCHEMBL18010744 | 0.84 | CPS1 (0.57) | HTTKDM4EALDH1A1CPS1LMNA | |
| SCHEMBL7872416 | 0.81 | CPS1 (0.57) | HTTKDM4EALDH1A1CPS1LMNA | |
| SCHEMBL7878686 | 0.81 | CPS1 (0.60) | HTTKDM4EALDH1A1CPS1LMNA | |
| SCHEMBL12205464 | 0.80 | CPS1 (0.58) | HTTALDH1A1CPS1LMNAMAPT | |
| SCHEMBL7870100 | 0.80 | CPS1 (0.59) | HTTALDH1A1CPS1LMNAMAPT | |
| SCHEMBL7870107 | 0.78 | CPS1 (0.54) | HTTKDM4EALDH1A1CPS1LMNA | |
| SCHEMBL23981747 | 0.78 | EPHX2 (0.50) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL30396995 | 0.78 | EPHX2 (0.50) | LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122069-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |