Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872390 | 1.00 | TDP1 (0.32) | TDP1HTTNPY5RKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7871576 | 0.99 | TDP1 (0.32) | TDP1HTTNPY5R | |
| Hydrochloric Acid SCHEMBL7871630 | 0.99 | TDP1 (0.32) | TDP1HTTNPY5R | |
| SCHEMBL7872380 | 0.99 | HTT (0.32) | TDP1HTTNPY5RKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7875443 | 0.98 | HTT (0.31) | TDP1HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7863434 | 0.96 | HTT (0.32) | HTTKDM4EALDH1A1CYP1A2POLB | |
| Hydrochloric Acid SCHEMBL7869002 | 0.95 | HTT (0.32) | HTTKDM4EALDH1A1CYP1A2POLB | |
| SCHEMBL7863469 | 0.89 | EPHX1 (0.37) | TDP1HTTNPY5RKDM4EALDH1A1 | |
| SCHEMBL7871635 | 0.89 | EPHX1 (0.37) | TDP1HTTNPY5RKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7871603 | 0.88 | EPHX1 (0.36) | TDP1HTTNPY5RKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010051631-A1 | Tricyclic compounds, their production and use | TAKATANI MUNEO (JP) | 2001-12-13 | — | — | US | disclosed |
| US-6251905-B1 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0771319-A1 | TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996002542-A1 | TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051631-A1 | Tricyclic compounds, their production and use | PDGFA, HGF, REN | TDP1 2771/4885HTT 710/4885NPY5R 1237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.