Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871686 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPK1CA12CA1CA7 | |
| SCHEMBL7249235 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPK1CA12CA1CA7 | |
| SCHEMBL7871728 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPK1CA12CA1CA7 | |
| SCHEMBL7246656 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1CA12CA1CA7 | |
| SCHEMBL7170109 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPK1CA12CA1CA7 | |
| SCHEMBL7247052 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPK1CA12CA1CA7 | |
| SCHEMBL7873630 | 0.74 | ALDH1A1 (0.37) | ALDH1A1MAPK1CA12CA1CA7 | |
| SCHEMBL7873629 | 0.74 | ALDH1A1 (0.37) | ALDH1A1MAPK1CA12CA1CA7 | |
| SCHEMBL7877695 | 0.74 | ALDH1A1 (0.37) | ALDH1A1MAPK1CA12CA1CA7 | |
| SCHEMBL31036121 | 0.69 | CA12 (0.55) | ALDH1A1MAPK1CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313320-B1 | DESULFONATION, DEBLOCKING, DEPROTECTING; VIRICIDES | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-11-06 | — | — | US | disclosed |