Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873630 | 1.00 | ALDH1A1 (0.37) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL7873629 | 1.00 | ALDH1A1 (0.37) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL7873539 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL7871684 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL7871686 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL7877692 | 0.67 | ALDH1A1 (0.32) | ALDH1A1KDM4EHSD17B10KMT2ANPSR1 | |
| SCHEMBL7873625 | 0.67 | ALDH1A1 (0.32) | ALDH1A1KDM4EHSD17B10KMT2ANPSR1 | |
| SCHEMBL7170109 | 0.61 | ALDH1A1 (0.56) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL7249235 | 0.59 | ALDH1A1 (0.53) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL13261902 | 0.58 | ALDH1A1 (0.51) | ALDH1A1HTTKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313320-B1 | DESULFONATION, DEBLOCKING, DEPROTECTING; VIRICIDES | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-11-06 | — | — | US | disclosed |
| WO-2000064902-A2 | PROCESS FOR THE PREPARATION OF CALANOLIDE PRECURSORS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |