SCHEMBL787175

SCHEMBL787175

Cc1cccc2c1oc1c(-c3ccc4[nH]c5ccc(-c6cccc7c6oc6c(C)cccc67)cc5c4c3)cccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
KIF11 P52732 3/20 0.36
TRPA1 O75762 1/20 0.35
MCL1 Q07820 1/20 0.35
GRIA1 P42261 1/20 0.35
CACNG8 Q8WXS5 1/20 0.35
ADORA3 P0DMS8 2/20 0.35
KDM4E B2RXH2 3/20 0.34
MAPT P10636 2/20 0.34
ATM Q13315 1/20 0.34
ACVR1 Q04771 1/20 0.34
PRKDC P78527 1/20 0.34
TNKS2 Q9H2K2 2/20 0.33
TLR8 Q9NR97 1/20 0.33
TLR7 Q9NYK1 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
TNKS O95271 1/20 0.33
AHR P35869 1/20 0.33
ADORA2A P29274 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788294 0.96 KIF11 (0.43) ALOX5KIF11TRPA1KDM4EMAPT
SCHEMBL10226912 0.88 ALOX5 (0.40) ALOX5KIF11ADORA3KDM4EMAPT
SCHEMBL787205 0.86 ALOX5 (0.37) ALOX5KIF11TRPA1GRIA1CACNG8
SCHEMBL786991 0.85 ALOX5 (0.46) ALOX5KIF11KDM4EPRKDCAHR
SCHEMBL787005 0.85 KIF11 (0.46) ALOX5KIF11KDM4EMAPTATM
SCHEMBL787222 0.84 ALOX5 (0.44) ALOX5KIF11KDM4EPRKDCAHR
SCHEMBL787375 0.83 KIF11 (0.39) ALOX5KIF11KDM4EMAPTATM
SCHEMBL12799833 0.82 ALOX5 (0.44) ALOX5MCL1ADORA3PRKDCMAOA
SCHEMBL10227375 0.82 ALOX5 (0.36) ALOX5PRKDCTLR8TLR7
SCHEMBL10226911 0.82 ALOX5 (0.43) ALOX5KIF11KDM4EMAPTPRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885KIF11 1085/4885TRPA1 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.