Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.65 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | LAP3 | P28838 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TPH1 | P17752 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426450 | 1.00 | LDHA (0.65) | LDHALTA4HSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL20027598 | 0.87 | LDHA (0.56) | LDHALTA4HSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL7961571 | 0.86 | LTA4H (0.69) | LDHALTA4HSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL12379291 | 0.83 | LTA4H (0.57) | LTA4HPPARGPPARALAP3 | |
| SCHEMBL5812622 | 0.81 | PPARG (0.48) | LTA4HPPARGPPARALAP3KMT2A | |
| SCHEMBL158667 | 0.81 | LDHA (0.71) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL126195 | 0.81 | LDHA (0.71) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL597743 | 0.81 | LDHA (0.71) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7432229 | 0.81 | LDHA (0.54) | LDHALTA4HSLC6A4LAP3 | |
| SCHEMBL7432217 | 0.81 | LDHA (0.54) | LDHALTA4HSLC6A4LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1774635-A | Anti-epileptogenic agents | UNIV KINGSTON (CA) | 2006-05-17 | — | — | CN | disclosed |
| US-6329502-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OF AIDS (ACQUIRED IMMUNE DEFICIENCY SYNDROME) | JAPAN ENERGY CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0490667-B1 | HIV protease inhibitors | JAPAN ENERGY CORP (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |