Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12101718 | 0.90 | NPC1 (0.51) | NPC1POLBMAPTRAB9AHDAC1 | |
| SCHEMBL28442966 | 0.84 | RARB (0.51) | NPC1POLBMAPTRAB9AALDH1A1 | |
| SCHEMBL16386159 | 0.83 | RAB9A (0.47) | NPC1POLBMAPTRAB9AKDM4E | |
| SCHEMBL13905148 | 0.83 | CYP1A2 (0.50) | NPC1POLBMAPTRAB9AHTT | |
| SCHEMBL12643380 | 0.81 | PKM (0.47) | NPC1POLBMAPTRAB9AHDAC1 | |
| SCHEMBL12462603 | 0.81 | MAPT (0.44) | NPC1POLBMAPTRAB9AHDAC1 | |
| SCHEMBL2145971 | 0.81 | ALDH1A1 (0.57) | NPC1POLBMAPTRAB9AHDAC1 | |
| SCHEMBL5353233 | 0.81 | PKM (0.55) | NPC1POLBMAPTRAB9AHDAC1 | |
| SCHEMBL6689465 | 0.81 | MAPT (0.49) | NPC1POLBMAPTRAB9AHDAC1 | |
| SCHEMBL29106631 | 0.81 | NPC1 (0.49) | NPC1POLBMAPTRAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095931-A1 | Benzidine derivatives and electrophotosensitive material using the same | KYOCERA MITA CORPORATION (JP) | 2001-05-02 | — | — | EP | disclosed |
| EP-0648737-B1 | Benzidine derivatives and electrophotosensitive material using the same | MITA INDUSTRIAL CO LTD (JP) | 1998-07-15 | — | — | EP | disclosed |
| EP-0799818-A2 | Benzidine derivatives and electrophotosensitive material using the same | MITA INDUSTRIAL CO. LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5550290-A | CHARGE TRANSFER COMPOUND | MITA INDUSTRIAL CO. LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0648737-A1 | Benzidine derivatives and electrophotosensitive material using the same | MITA INDUSTRIAL CO. LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |