Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676012 | 0.85 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A | |
| SCHEMBL1837157 | 0.78 | GABRA1 (0.46) | ALDH1A1CYP1A2 | |
| SCHEMBL908326 | 0.77 | POLB (0.40) | ACP3METAP2METAP1SSTR4 | |
| SCHEMBL14720630 | 0.76 | CYP19A1 (0.52) | ACP3METAP2METAP1SSTR4 | |
| SCHEMBL14720629 | 0.76 | CYP19A1 (0.52) | ACP3METAP2METAP1SSTR4 | |
| SCHEMBL1846694 | 0.76 | GABRA1 (0.47) | ALDH1A1CYP1A2SLC6A2SLC6A4 | |
| SCHEMBL14667605 | 0.74 | SLC18A2 (0.47) | METAP2CYP1A2CYP2C19 | |
| SCHEMBL1837910 | 0.74 | GABRA1 (0.34) | ALDH1A1CYP1A2SLC6A2 | |
| SCHEMBL30409561 | 0.74 | GABRA1 (0.34) | ALDH1A1CYP1A2SLC6A2 | |
| SCHEMBL15503588 | 0.74 | PPARG (0.40) | ACP3METAP2METAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087934-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | Nortran Pharmaceuticals Inc. (CA) | 2001-04-04 | — | — | EP | claimed |
| WO-1999050225-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | NORTRAN PHARMACEUTICALS INC. (CA) | 1999-10-07 | — | — | WO | claimed |
| EP-1087934-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | Nortran Pharmaceuticals Inc. (CA) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999050225-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | NORTRAN PHARMACEUTICALS INC. (CA) | 1999-10-07 | — | — | WO | disclosed |