Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.32 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777133 | 1.00 | ALDH1A1 (0.44) | ALDH1A1PTGS1MAPTSLC1A3SLC1A2 | |
| SCHEMBL5281249 | 0.80 | PTGS1 (0.48) | ALDH1A1PTGS1MAPTSLC1A3SLC1A2 | |
| SCHEMBL5144737 | 0.80 | PTGS1 (0.48) | ALDH1A1PTGS1MAPTSLC1A3SLC1A2 | |
| SCHEMBL10567437 | 0.76 | SLC1A3 (0.35) | ALDH1A1PTGS1MAPTSLC1A3SLC1A2 | |
| SCHEMBL4951671 | 0.73 | CPT2 (0.41) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL5288950 | 0.73 | ALDH1A1 (0.52) | ALDH1A1PTGS1MAPTSLC1A3SLC1A2 | |
| SCHEMBL9251690 | 0.73 | CPT2 (0.41) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL3821550 | 0.73 | ALDH1A1 (0.52) | ALDH1A1PTGS1MAPTSLC1A3SLC1A2 | |
| SCHEMBL11460744 | 0.73 | LMNA (0.36) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL1631413 | 0.73 | ALDH1A1 (0.52) | ALDH1A1PTGS1MAPTSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313095-B1 | HERPES VIRAL RIBONUCLEOTIDE REDUCTASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 2001-11-06 | — | — | US | disclosed |
| US-5830864-A | RIBONUCLEOTIDE REDUCTASE INHIBITOR | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 1998-11-03 | — | — | US | disclosed |
| EP-0560274-B1 | Antiherpes peptide derivatives having a ureido N-terminus | BOEHRINGER INGELHEIM CA LTD (CA) | 1998-06-24 | — | — | EP | disclosed |
| US-5484771-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-01-16 | — | — | US | disclosed |
| EP-0411333-B1 | Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-05-31 | — | — | EP | disclosed |
| EP-0461546-B1 | Antiherpes peptide derivatives having a 1,4-dioxo-C4 N-terminus | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-03-22 | — | — | EP | disclosed |
| CN-1096299-A | Antiherpes peptide derivatives with ureido N-terminus | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1994-12-14 | — | — | CN | disclosed |
| EP-0560274-A1 | Antiherpes peptide derivatives having a ureido N-terminus | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-15 | — | — | EP | disclosed |
| EP-0461546-A2 | Antiherpes peptide derivatives having a 1,4-dioxo-C4 N-terminus | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-12-18 | — | — | EP | disclosed |