Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872435 | 0.77 | F2 (0.47) | SGMS2ALDH1A1GAAKDM4E | |
| SCHEMBL7872355 | 0.77 | ABCB1 (0.54) | SGMS2ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL7868630 | 0.69 | CNR2 (0.46) | GAACYP1A2CYP2C19MME | |
| SCHEMBL7865908 | 0.69 | HTT (0.43) | CYP1A2CYP2C19MME | |
| SCHEMBL7865923 | 0.69 | MME (0.44) | SGMS2ALDH1A1GAAKDM4ECYP1A2 | |
| SCHEMBL1388008 | 0.69 | MRGPRX4 (0.59) | ALDH1A1GAAKDM4ESLC1A5ABCB1 | |
| SCHEMBL22351829 | 0.67 | CYP2D6 (0.65) | SLC1A5ABCB1HTR1ADRD2FFAR1 | |
| SCHEMBL22351827 | 0.67 | CYP2D6 (0.65) | SLC1A5ABCB1HTR1ADRD2FFAR1 | |
| SCHEMBL21793250 | 0.67 | CYP2D6 (0.48) | SLC1A5ABCB1HTR1ADRD2FFAR1 | |
| SCHEMBL7867488 | 0.67 | MME (0.43) | ALDH1A1CYP1A2CYP2C19MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086107-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065914-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA (CN) | 1999-12-23 | — | — | WO | disclosed |