Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872437 | 0.77 | SGMS2 (0.54) | ALDH1A1GAAKDM4ESGMS2 | |
| SCHEMBL7868991 | 0.77 | NPC1 (0.51) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7865912 | 0.74 | CYP1A2 (0.51) | KMT2AHDAC1HDAC8 | |
| SCHEMBL30839672 | 0.74 | MTNR1A (0.53) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL5687942 | 0.73 | KMT2A (0.59) | KMT2AMEN1GAAMTNR1AMTNR1B | |
| SCHEMBL10826668 | 0.73 | NPC1 (0.47) | F2F10PRSS1F7PRSS2 | |
| Hydrochloric Acid SCHEMBL5742387 | 0.73 | NPC1 (0.50) | F2F10PRSS1F7PRSS2 | |
| Hydrochloric Acid SCHEMBL5742389 | 0.73 | NPC1 (0.50) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL9808697 | 0.73 | HPGD (0.59) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL5685487 | 0.72 | KMT2A (0.52) | SMN1; SMN2KMT2AMTNR1AMTNR1BAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086107-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065914-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA (CN) | 1999-12-23 | — | — | WO | disclosed |