Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 8/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856559 | 0.80 | SGMS2 (0.53) | HTR1ASGMS2ALDH1A1LMNAGAA | |
| SCHEMBL7872437 | 0.77 | SGMS2 (0.54) | ABCB1HTR1ADRD2SGMS2ALDH1A1 | |
| SCHEMBL2580244 | 0.76 | MAOB (0.55) | ABCB1HTR1ADRD2SGMS2ALDH1A1 | |
| SCHEMBL22144397 | 0.76 | TSHR (0.47) | SGMS2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL1199570 | 0.76 | TSHR (0.47) | SGMS2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL1200542 | 0.75 | CTDSP1 (0.46) | SGMS2ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL12301142 | 0.74 | ABCB1 (0.67) | ABCB1HTR1ADRD2ADRA1DADRA1A | |
| SCHEMBL9229299 | 0.74 | TAAR1 (0.51) | ABCB1HTR1ADRD2SGMS2ALDH1A1 | |
| SCHEMBL29957299 | 0.73 | ENPP2 (0.68) | ABCB1HTR1ADRD2ADRA1DADRA1A | |
| SCHEMBL5643074 | 0.73 | ABCB1 (0.74) | ABCB1HTR1ADRD2ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307068-B1 | TREATING OR IN PREVENTING CANCER. | ADIR ET COMPAGNIE (FR) | 2001-10-23 | — | — | US | disclosed |