Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15404816 | 0.85 | TDP1 (0.45) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL3101729 | 0.82 | TDP1 (0.47) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL17320926 | 0.82 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL7161569 | 0.82 | THRB (0.47) | TDP1TSHRTHRBPPARACHRM2 | |
| SCHEMBL234086 | 0.80 | POLB (0.41) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL3309534 | 0.78 | AKR1B10 (0.39) | PPARA | |
| SCHEMBL3684293 | 0.76 | THRB (0.39) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL13801023 | 0.76 | POLB (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL12227048 | 0.76 | POLB (0.41) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL28552216 | 0.76 | POLB (0.44) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6309708-B1 | ORGANOMETALLIC POLYMERS | DAIKIN INDUSTRIES, LTD. (JP) | 2001-10-30 | — | — | US | disclosed |