Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31702150 | 0.92 | TDP1 (0.46) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL2479797 | 0.92 | TDP1 (0.46) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL2596256 | 0.87 | TDP1 (0.42) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL32679322 | 0.85 | TDP1 (0.46) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL18112975 | 0.85 | TDP1 (0.46) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL18905090 | 0.84 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL14578462 | 0.84 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29580289 | 0.84 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL123793 | 0.84 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL8967138 | 0.82 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62114941-A | — | — | None | — | — | JP | disclosed |
| US-12485169-B2 | Compounds | Grey Wolf Therapeutics Limited (GB) | 2025-12-02 | — | — | US | disclosed |
| US-20250333399-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KHORA SPV 1 LLC (US) | 2025-10-30 | — | — | US | disclosed |
| US-20250223300-A1 | MACROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | BETTA PHARMACEUTICALS CO LTD (CN) | 2025-07-10 | — | — | US | disclosed |
| US-12331039-B2 | Inhibitors of fibroblast growth factor receptor kinases | KHORA SPV 1, LLC (US) | 2025-06-17 | — | — | US | disclosed |
| EP-4559920-A1 | MACROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2025-05-28 | — | — | EP | disclosed |
| CN-120025279-A | Compounds capable of modulating endoplasmic reticulum aminopeptidase 1 | 格雷沃尔夫治疗有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-119998278-A | Compounds and uses thereof | 福宏治疗公司 | 2025-05-13 | — | — | CN | disclosed |
| US-12264147-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | Propellon Therapeutics Inc. (CA) | 2025-04-01 | — | — | US | disclosed |
| EP-4522278-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| US-9221816-B2 | 2-oxo-2,3-dihydro-indoles for the treatment of CNS disorders | HOFFMANN LA-ROCHE INC. (US) | 2015-12-29 | — | — | US | disclosed |
| CN-105164112-A | Amide compound and preparation method, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-12-16 | — | — | CN | disclosed |
| US-20150284386-A1 | 2-OXO-2,3-DIHYDRO-INDOLES FOR THE TREATMENT OF CNS DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 2015-10-08 | — | — | US | disclosed |
| EP-2895476-A1 | 2-OXO-2,3-DIHYDRO-INDOLES FOR THE TREATMENT OF CNS DISORDERS | F. Hoffmann-La Roche AG (CH) | 2015-07-22 | — | — | EP | disclosed |
| US-20140319507-A1 | Organic Electroluminescent Element, Material for Organic Electroluminescent Element, Light Emitting Device, Display Device and Lighting Device Each Using Said Element, and Compound Used for Said Element | UDC IRELAND LIMITED (IE) | 2014-10-30 | — | — | US | disclosed |
| WO-2014040969-A1 | 2-OXO-2,3-DIHYDRO-INDOLES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-03-20 | — | — | WO | disclosed |
| CN-1244542-C | Aromatic amine derivatives having NOS inhibitory effect | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2006-03-08 | — | — | CN | disclosed |
| US-6331553-B1 | INHIBITORS OF NITRIC OXIDE SYNTHASE; TREATING CEREBROVASCULAR DISEASES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-12-18 | — | — | US | disclosed |
| EP-0949242-A1 | AROMATIC AMINE DERIVATIVES HAVING NOS INHIBITORY EFFECT | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-10-13 | — | — | EP | disclosed |
| JP-S62114941-A | 5-BROMO-4-CHLORO-2-FLUOROANILINE AND PRODUCTION THEREOF | SUMITOMO CHEM CO LTD | 1987-05-26 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12264147-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | WDR5, WDR82, WDR1 | TDP1 3050/4885ATM 3350/4885ALDH1A1 3236/4885 |
| US-12331039-B2 | Inhibitors of fibroblast growth factor receptor kinases | FGFR1, FGFR2, FGFR3 | TDP1 2063/4885ATM 484/4885ALDH1A1 2169/4885 |
| US-20250333399-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | FGFR1, FGFR2, FGFR3 | TDP1 2063/4885ATM 484/4885ALDH1A1 2169/4885 |
| US-12485169-B2 | Compounds | SLC10A1, VHL, CFTR | TDP1 1403/4885ATM 991/4885ALDH1A1 276/4885 |
| US-20250223300-A1 | MACROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | EGFR, ERBB3, ERBB2 | TDP1 4371/4885ATM 723/4885ALDH1A1 3526/4885 |
| US-20150284386-A1 | 2-OXO-2,3-DIHYDRO-INDOLES FOR THE TREATMENT OF CNS DISORDERS | HCRTR2, TPH2, CNR2 | TDP1 2939/4885ATM 4565/4885ALDH1A1 1145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.