Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.44 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578462 | 1.00 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29580289 | 1.00 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL432601 | 0.89 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL30434858 | 0.89 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL138641 | 0.89 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29739925 | 0.89 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL30953155 | 0.89 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL8967138 | 0.89 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL9694173 | 0.84 | TSHR (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL811001 | 0.84 | ALDH1A1 (0.53) | TDP1ATMALDH1A1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117509803-A | Treatment device and treatment method for 2, 4-dichloro-5-fluoronitrobenzene waste acid mother liquor | 浙江工业大学 | 2024-02-06 | — | — | CN | claimed |
| CN-116514723-A | Synthesis method of 5, 6-2-chloro-1-ethyl-1H-benzimidazole-2-one (DCEBIO) | 上海麦克林生化科技股份有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-102911080-B | Method for preparing 2,6-dichloro-alpha-(4-chlorphenyl)-4-nitro phenylacetonitrile | UNIV QUZHOU | 2015-01-21 | — | — | CN | claimed |
| CN-103420842-B | Preparation method for 2,3,4-trifluoronitrobenzene | SHANGYU LINJIANG CHEMICAL CO LTD | 2015-01-07 | — | — | CN | claimed |
| CN-102796003-B | Preparation method of 2-fluoro-4,5-dichloronitrobenzene | UNIV CHANGZHOU | 2014-05-28 | — | — | CN | claimed |
| EP-4702021-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| US-12310975-B2 | Modulators of BCL6 proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2025-05-27 | — | — | US | disclosed |
| US-20240376059-A1 | Compounds for the Treatment of Alzheimer's Disease | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2024-11-14 | — | — | US | disclosed |
| WO-2024224064-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2024-10-31 | — | — | WO | disclosed |
| US-20240327383-A1 | PIPERIDINE DERIVATIVE, AND PHARMACEUTIAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | Yichang Humanwell Pharmaceutical Co., Ltd. (CN) | 2024-10-03 | — | — | US | disclosed |
| CN-115611856-B | Piperidine derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-07-05 | — | — | CN | disclosed |
| US-20240150287-A1 | N-(BENZOYL)-PHENYLALANINE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | HANGZHOU APELOA MEDICINE RESEARCH INSTITUTE CO., LTD. (CN) | 2024-05-09 | — | — | US | disclosed |
| US-5545669-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORPORATION | 1996-08-13 | — | — | US | disclosed |
| WO-1995033461-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| WO-1995033715-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| EP-0477819-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-03-15 | — | — | EP | disclosed |
| US-5200422-A | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-04-06 | — | — | US | disclosed |
| EP-0270964-B1 | PROCESS FOR OBTAINING SUBSTITUTED FLUOROBENZENES | BAYER AG (DE) | 1992-07-08 | — | — | EP | disclosed |
| EP-0477819-A2 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1992-04-01 | — | — | EP | disclosed |
| US-4868347-A | SOLVENT EXTRACTION | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327383-A1 | PIPERIDINE DERIVATIVE, AND PHARMACEUTIAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | OPRL1, OPRD1, OPRM1 | TDP1 2672/4885ATM 4844/4885ALDH1A1 188/4885 |
| US-20240150287-A1 | N-(BENZOYL)-PHENYLALANINE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | ITGB7, ITGB4, ITGA4 | TDP1 3499/4885ATM 4513/4885ALDH1A1 988/4885 |
| US-12310975-B2 | Modulators of BCL6 proteolysis and associated methods of use | BCL6, BCL6B, BCL3 | TDP1 1700/4885ATM 2479/4885ALDH1A1 3306/4885 |
| US-20240376059-A1 | Compounds for the Treatment of Alzheimer's Disease | IAPP, GPR119, APP | TDP1 1690/4885ATM 1025/4885ALDH1A1 4515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.