Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | RPA1 | P27694 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867813 | 0.91 | PTGS2 (0.44) | RPA1PTGS2PTGS1TUBB4ATUBB | |
| SCHEMBL7878950 | 0.84 | PTGS2 (0.43) | RPA1PTGS2PTGS1GABRPGABRD | |
| SCHEMBL1015933 | 0.84 | DYRK1A (0.48) | RIPK2DYRK1ARPA1PTGS2PTGS1 | |
| SCHEMBL8199732 | 0.82 | RPA1 (0.65) | RPA1 | |
| SCHEMBL7876568 | 0.82 | POLB (0.46) | RPA1PTGS2PTGS1GABRPGABRD | |
| SCHEMBL7465856 | 0.82 | PTGS2 (0.54) | RPA1PTGS2PTGS1CYP1A2CYP3A4 | |
| SCHEMBL8645116 | 0.81 | MALT1 (0.50) | RPA1PTGS2PTGS1CYP1A2CYP3A4 | |
| SCHEMBL7878991 | 0.81 | KDM4E (0.42) | PTGS2PTGS1 | |
| SCHEMBL7867770 | 0.80 | MAPT (0.45) | RIPK2RPA1PTGS2PTGS1CYP1A2 | |
| SCHEMBL7874517 | 0.79 | RPA1 (0.43) | RPA1PTGS2PTGS1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316485-B1 | INHIBITS ACTIVITY OF CYCLOOXYGENASE-2; FOR THERAPY AND PROPHYLAXIS OF INFLAMMATION, THROMBOSIS, RHEUMATOID ARTHRITIS, ALZHEIMER'S DISEASE; AS ANALGESIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |