Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | AHCY | P23526 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281840 | 0.83 | FDPS (0.45) | FGFR1FGFR4FDPSHDAC6P2RX7 | |
| SCHEMBL21539218 | 0.76 | ADORA2A (0.51) | FGFR1FGFR4FDPSP2RX7ADORA2A | |
| SCHEMBL21127815 | 0.76 | ADORA2A (0.46) | FGFR1FGFR4FDPSHDAC6P2RX7 | |
| SCHEMBL9536725 | 0.74 | FGFR1 (0.45) | FGFR1FGFR4FDPSHDAC6P2RX7 | |
| SCHEMBL11596964 | 0.74 | ADORA2A (0.45) | FGFR1FGFR4FDPSP2RX7ADORA2A | |
| SCHEMBL11258096 | 0.73 | ADORA2A (0.47) | FGFR1FGFR4FDPSP2RX7ADORA2A | |
| SCHEMBL2475932 | 0.73 | ADORA2A (0.64) | FGFR1FGFR4FDPSADORA2AADORA2B | |
| SCHEMBL31331738 | 0.73 | ADORA2A (0.64) | FGFR1FGFR4FDPSADORA2AADORA2B | |
| SCHEMBL11596392 | 0.71 | ADORA2A (0.49) | FGFR1FGFR4FDPSHDAC6P2RX7 | |
| SCHEMBL7867778 | 0.71 | CCNB2 (0.38) | FGFR1FGFR4HDAC6ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |