Phenol

Phenol

SCHEMBL7872891

Cc1ccc([P+](c2ccc(C)cc2)(c2ccc(C)cc2)c2ccc(C)cc2)cc1.[O-]c1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 3/20 0.43
ACHE P22303 2/20 0.43
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.43
HPGD P15428 4/20 0.38
TDP1 Q9NUW8 4/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
CA12 O43570 3/20 0.35
CA9 Q16790 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
ATM Q13315 1/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
MAPT P10636 2/20 0.34
HKDC1 Q2TB90 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404005 0.85 ACHE (0.53) ALOX12ACHELMNATSHRHPGD
Hydrochloric Acid SCHEMBL7058630 0.83 ACHE (0.50) ALOX12ACHELMNATSHRHPGD
Bromide SCHEMBL7063570 0.83 ACHE (0.50) ALOX12ACHELMNATSHRHPGD
Iodide SCHEMBL7065210 0.83 LMNA (0.50) ALOX12ACHELMNATSHRHPGD
Tetraphenylphosphonium SCHEMBL28123051 0.83 HIF1A (0.39) TSHRHPGDTDP1CYP1A2CYP3A4
Tetraphenylphosphonium SCHEMBL49763 0.83 HIF1A (0.39) TSHRHPGDTDP1CYP1A2CYP3A4
SCHEMBL7065117 0.83 ACHE (0.40) ALOX12ACHELMNATSHRHPGD
SCHEMBL11314306 0.82 ACHE (0.43) ALOX12ACHELMNATSHRHPGD
SCHEMBL49568 0.81 ACHE (0.32) ACHETDP1
SCHEMBL28362175 0.80 ACHE (0.44) ALOX12ACHELMNATSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed