Biphenyl

Biphenyl

SCHEMBL7872898

CO.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1.c1ccc(Pc2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
SLC22A2 O15244 1/20 0.40
SLC22A1 O15245 1/20 0.40
SLC22A3 O75751 1/20 0.40
SLC6A4 P31645 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
MGLL Q99685 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
CA12 O43570 1/20 0.38
GLA P06280 1/20 0.38
CA3 P07451 1/20 0.38
CA4 P22748 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CYP1A2 P05177 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL10535523 0.91 ALDH1A1 (0.60) ALDH1A1MMP3BCL2L1SMN1; SMN2SLC22A2
Methyl Alcohol SCHEMBL28288466 0.91 CA2 (0.44) ALDH1A1MMP3BCL2L1CA1CA2
Biphenyl SCHEMBL27082161 0.91 ALDH1A1 (0.60) ALDH1A1MMP3BCL2L1SMN1; SMN2SLC22A2
Biphenyl SCHEMBL7868148 0.88 ALDH1A1 (0.56) ALDH1A1MMP3BCL2L1SMN1; SMN2SLC22A2
Biphenyl SCHEMBL7871107 0.88 ALDH1A1 (0.56) ALDH1A1MMP3BCL2L1SMN1; SMN2SLC22A2
Biphenyl SCHEMBL4388996 0.88 ALDH1A1 (0.56) ALDH1A1MMP3BCL2L1SMN1; SMN2SLC22A2
Biphenyl SCHEMBL7877163 0.88 ALDH1A1 (0.56) ALDH1A1MMP3BCL2L1SMN1; SMN2SLC22A2
Biphenyl SCHEMBL7871110 0.87 BCL2L1 (0.44) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL7874548 0.87 SMN1; SMN2 (0.52) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL7871046 0.86 MMP3 (0.62) ALDH1A1MMP3BCL2L1MAPTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed