SCHEMBL2819946

SCHEMBL2819946

NCC(=O)NCC(=O)N(CC(=O)O)C(=O)CS

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633350 0.88 GLRA1 (0.32) TERT
SCHEMBL7872934 0.87
SCHEMBL6841493 0.81 GLRA1 (0.30)
SCHEMBL1493219 0.80 GLRA1 (0.38)
SCHEMBL4734227 0.79 TERT (0.31) TERT
SCHEMBL27606643 0.77 MEN1 (0.31)
SCHEMBL11764044 0.74
SCHEMBL24065976 0.74 MVD (0.36) TERT
SCHEMBL3379494 0.74 GLRA1 (0.32) TERT
SCHEMBL468872 0.72 PAOX (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2301962-B1 Invention affecting GLP-1 and Exendin UNIV MARBURG PHILIPPS (DE) 2013-10-30 EP claimed
EP-2070946-B1 Invention affecting GLP-1 and Exendin UNIV MARBURG PHILIPPS (DE) 2013-05-29 EP claimed
US-20130095037-A1 PEPTIDE DERIVATIVES OF EXENDIN-4 PHILIPPS-UNIVERSITAT MARBURG (DE) 2013-04-18 US claimed
US-8268781-B2 Peptide derivatives of exendin-4 PHILIPPS-UNIVERSITAT MARBURG (DE) 2012-09-18 US claimed
US-20090180953-A1 Invention concerning GLP-1 and exendin PHILIPPS-UNIVERSITAT MARBURG (DE) 2009-07-16 US claimed
EP-1784422-A2 GLP-1 AND EXENDIN RELATED INVENTION Philipps-Universität Marburg (DE) 2007-05-16 EP claimed
WO-2006024275-A2 GLP-1 AND EXENDIN RELATED INVENTION PHILIPPS-UNIVERSITÄT MARBURG (DE) 2006-03-09 WO claimed
EP-4556029-A2 RADIOPHARMACEUTICAL CONJUGATE The South African Nuclear Energy Corporation Limited (ZA) 2025-05-21 EP disclosed
CN-107106709-B Radiopharmaceutical conjugates comprising a metabolite and an EPR agent targeting tumor cells 南非核能源有限公司 2021-04-06 CN disclosed
US-10874753-B2 Radiopharmaceutical conjugate of a metabolite and an EPR agent, for targeting tumour cells THE SOUTH AFRICAN NUCLEAR ENERGY CORPORATION LIMITED (ZA) 2020-12-29 US disclosed
US-20170296684-A1 RADIOPHARMACEUTICAL CONJUGATE UNIVERSITY OF CAPE TOWN (ZA) 2017-10-19 US disclosed
EP-3197504-A2 RADIOPHARMACEUTICAL CONJUGATE OF A METABOLITE AND AN EPR AGENT, FOR TARGETING TUMOUR CELLS The South African Nuclear Energy Corporation Limited (ZA) 2017-08-02 EP disclosed
WO-2016046793-A2 RADIOPHARMACEUTICAL CONJUGATE THE SOUTH AFRICAN NUCLEAR ENERGY CORPORATION LIMITED (ZA) 2016-03-31 WO disclosed
US-20090180953-A1 Invention concerning GLP-1 and exendin PHILIPPS-UNIVERSITAT MARBURG (DE) 2009-07-16 US disclosed
EP-2070946-A2 Invention affecting GLP-1 and Exendin Philipps-Universität Marburg (DE) 2009-06-17 EP disclosed
EP-1784422-A2 GLP-1 AND EXENDIN RELATED INVENTION Philipps-Universität Marburg (DE) 2007-05-16 EP disclosed
WO-2006024275-A2 GLP-1 AND EXENDIN RELATED INVENTION PHILIPPS-UNIVERSITÄT MARBURG (DE) 2006-03-09 WO disclosed
EP-0963182-A4 METHOD OF TREATING A DISEASE PROCESS IN A LUMINAL STRUCTURE UNIV COLUMBIA (US) 2000-10-18 EP disclosed
EP-0963182-A1 METHOD OF TREATING A DISEASE PROCESS IN A LUMINAL STRUCTURE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1999-12-15 EP disclosed
WO-1998012979-A1 METHOD OF TREATING A DISEASE PROCESS IN A LUMINAL STRUCTURE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1998-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10874753-B2 Radiopharmaceutical conjugate of a metabolite and an EPR agent, for targeting tumour cells EPRS1, FOLH1, SLC46A1 TERT 2273/4885
US-20170296684-A1 RADIOPHARMACEUTICAL CONJUGATE FOLH1, EPRS1, FOLR1 TERT 2851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.