Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198029 | 0.85 | F2 (0.50) | CES1MAPTKMT2AALOX15CYP3A4 | |
| SCHEMBL3069331 | 0.84 | ALDH1A1 (0.55) | MAPTKMT2AALOX15MEN1KDM4E | |
| SCHEMBL17734061 | 0.82 | CES1 (0.46) | CES1MAPTKMT2AALOX15CYP3A4 | |
| SCHEMBL16443664 | 0.82 | CA1 (0.50) | MAPTKMT2ACYP3A4MEN1HPGD | |
| SCHEMBL3862551 | 0.80 | MASP2 (0.46) | MAPTKMT2ACYP3A4TDP1MEN1 | |
| SCHEMBL34464716 | 0.80 | CES2 (0.48) | CES1MAPTKMT2ACYP3A4MEN1 | |
| SCHEMBL10814700 | 0.80 | TSHR (0.54) | CES1MAPTKMT2AALOX15CYP3A4 | |
| SCHEMBL15589115 | 0.80 | F2 (0.46) | CES1MAPTKMT2AALOX15CYP3A4 | |
| SCHEMBL11132893 | 0.80 | CES1 (0.50) | CES1MAPTKMT2AALOX15CYP3A4 | |
| Toluene SCHEMBL10507527 | 0.80 | SMN1; SMN2 (0.53) | CES1MAPTKMT2ACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497734-B1 | Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines | CIBA SC HOLDING AG (CH) | 2000-05-10 | — | — | EP | claimed |
| US-5463048-A | Immunosuppressive, antiinflammatory, antifungal, antitumor, antiproliferative agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-31 | — | — | US | claimed |
| US-5182389-A | PROCESS FOR THE PREPARATION OF 2-(2',4'-DIHYDROXYPHENYL)-4,6-DIARYL-S-TRIAZINES | CIBA-GEIGY CORPORATION (US) | 1993-01-26 | — | — | US | claimed |
| EP-0765329-B1 | RAPAMYCIN AMIDINO CARBAMATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PROD (US) | 2001-08-16 | — | — | EP | disclosed |
| US-5637590-A | Rapamycin amidino carbamates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0765329-A1 | RAPAMYCIN AMIDINO CARBAMATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-04-02 | — | — | EP | disclosed |
| US-5541192-A | Rapamycin amidino carbamates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| US-5541191-A | Rapamycin amidino carbamates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| US-5508286-A | Rapamycin amidino carbamates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| WO-1995034565-A1 | RAPAMYCIN AMIDINO CARBAMATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-12-21 | — | — | WO | disclosed |
| US-5463048-A | Immunosuppressive, antiinflammatory, antifungal, antitumor, antiproliferative agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0406760-B1 | Plant growth regulating composition | SUMITOMO CHEMICAL CO (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0052819-B1 | PROCESS FOR PREPARING AMIDINECARBOXYLIC ACIDS | UBE INDUSTRIES, LTD. (JP) | 1984-02-29 | — | — | EP | disclosed |
| US-4375554-A | REACTING AN ALKOXYIMINOACETIC ACID ESTER WITH A PRIMARY AMINE | UBE INDUSTRIES LTD. (JP) | 1983-03-01 | — | — | US | disclosed |
| EP-0052819-A1 | Process for preparing amidinecarboxylic acids | UBE INDUSTRIES, LTD. (JP) | 1982-06-02 | — | — | EP | disclosed |