Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.39 |
| ▸ | CKS1B | P61024 | 7/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 7/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29026621 | 0.99 | TOP2A (0.38) | TOP2ACKS1BSKP2GLO1MMP2 | |
| Water SCHEMBL8819292 | 0.99 | TOP2A (0.38) | TOP2ACKS1BSKP2GLO1MMP2 | |
| SCHEMBL597833 | 0.99 | TOP2A (0.40) | TOP2ACKS1BSKP2GLO1MMP2 | |
| SCHEMBL870765 | 0.99 | TOP2A (0.40) | TOP2ACKS1BSKP2GLO1MMP2 | |
| SCHEMBL6037850 | 0.98 | TOP2A (0.39) | TOP2ACKS1BSKP2GLO1MMP2 | |
| SCHEMBL27805381 | 0.98 | TOP2A (0.39) | TOP2ACKS1BSKP2GLO1MMP2 | |
| SCHEMBL15570898 | 0.93 | TOP2A (0.36) | TOP2ACKS1BSKP2GLO1MMP2 | |
| SCHEMBL4892330 | 0.91 | TOP2A (0.38) | TOP2ACKS1BSKP2GLO1MMP2 | |
| SCHEMBL3964610 | 0.82 | CKS1B (0.36) | TOP2ACKS1BSKP2GLO1MMP2 | |
| SCHEMBL8140844 | 0.82 | CKS1B (0.38) | TOP2ACKS1BSKP2GLO1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3216788-A1 | ALPHA-HYDROXY-BETA-TRIAZOLO-TETRAZOLES | Centre National De La Recherche Scientifique (FR) | 2017-09-13 | — | — | EP | claimed |
| EP-0170414-B1 | PROCESS FOR TREATING METAL SURFACE | Hitachi Chemical Co., Ltd. (JP) | 1991-04-17 | — | — | EP | claimed |
| US-4643793-A | WITH MIXTURE OF COPPER COMPOUND, COMPLEXING AGENT, REDUCING AGENT, AND PH ADJUSTER IN PRESENCE OF NITROGEN HETEROCYCLE COMPOUND | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1987-02-17 | — | — | US | claimed |
| EP-0170414-A2 | Process for treating metal surface | Hitachi Chemical Co., Ltd. (JP) | 1986-02-05 | — | — | EP | claimed |
| US-10259838-B2 | Methods, compositions, and kits using heterogeneous catalysts | OCCIDENTAL COLLEGE (US) | 2019-04-16 | — | — | US | disclosed |
| US-9879044-B2 | Methods, compositions, and kits using heterogeneous catalysts | OCCIDENTAL COLLEGE (US) | 2018-01-30 | — | — | US | disclosed |
| US-20170327532-A1 | METHODS, COMPOSITIONS, AND KITS USING HETEROGENEOUS CATALYSTS | OCCIDENTAL COLLEGE | 2017-11-16 | — | — | US | disclosed |
| US-9765064-B1 | Alpha-hydroxy-beta-azido-tetrazoles | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-09-19 | — | — | US | disclosed |
| US-20170260171-A1 | ALPHA-HYDROXY-BETA-AZIDO-TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-09-14 | — | — | US | disclosed |
| EP-3216788-A1 | ALPHA-HYDROXY-BETA-TRIAZOLO-TETRAZOLES | Centre National De La Recherche Scientifique (FR) | 2017-09-13 | — | — | EP | disclosed |
| US-20160347785-A1 | METHODS, COMPOSITIONS, AND KITS USING HETEROGENEOUS CATALYSTS | OCCIDENTAL COLLEGE | 2016-12-01 | — | — | US | disclosed |
| CN-106028840-A | Mineral water composition containing bioavailable iron | 史诺多尼亚研究有限公司 | 2016-10-12 | — | — | CN | disclosed |
| WO-1999040424-A1 | WATER SOLUBLE LUMINESCENCE OXYGEN SENSOR AND METHOD | LAKOWICZ JOSEPH R (US) | 1999-08-12 | — | — | WO | disclosed |
| EP-0296686-B1 | A PROCESS FOR THE PREPARATION OF CARBAMATES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-04-01 | — | — | EP | disclosed |
| EP-0170414-B1 | PROCESS FOR TREATING METAL SURFACE | Hitachi Chemical Co., Ltd. (JP) | 1991-04-17 | — | — | EP | disclosed |
| EP-0296686-A1 | A process for the preparation of carbamates | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-12-28 | — | — | EP | disclosed |
| US-4643793-A | WITH MIXTURE OF COPPER COMPOUND, COMPLEXING AGENT, REDUCING AGENT, AND PH ADJUSTER IN PRESENCE OF NITROGEN HETEROCYCLE COMPOUND | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1987-02-17 | — | — | US | disclosed |
| EP-0170414-A2 | Process for treating metal surface | Hitachi Chemical Co., Ltd. (JP) | 1986-02-05 | — | — | EP | disclosed |
| EP-0061079-B1 | POLYMER STABILIZERS | GAF CORPORATION (US) | 1985-07-31 | — | — | EP | disclosed |
| US-4396734-A | VINYL POLYMER THICKENER, REDOX INDICATOR, MUCILAGE | GAF CORPORATION (US) | 1983-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260171-A1 | ALPHA-HYDROXY-BETA-AZIDO-TETRAZOLES | CYP8B1, HSD3B1, HSD17B1 | TOP2A 871/4885CKS1B 3449/4885SKP2 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.